eMule is a peer-to-peer file sharing application for Microsoft Windows. Started in May 2002 as an alternative to eDonkey2000, eMule now connects to both the eDonkey network and the Kad network.

In its common modern meaning, a mule is the offspring of a male donkey and a female horse. The reverse, the offspring of a male horse and a female donkey, is called a hinny. The term "mule" (Latin mulus) was formerly applied to the offspring of any two creatures of different species – in modern usage, a "hybrid".